Life Sciences &
Biotechnology

 




Leading Researchers:

Guided Regeneration Gel: A novel biocompatible hydrogel for peripheral nerve reconstruction and wound healing

The Technology Guided regeneration gel (GRG) is a novel biocompatible, biodegradable hydrogel for peripheral nerve reconstruction, cell therapy and wound healing. Similar to the extracellular matrix (ECM), GRG is transparent, highly viscous, malleab Read More >

Oncomir expression directed targeted chemotherapy

The InventionMicroRNAs (miRNAs) are an abundant class of short endogenous noncoding RNAs that act as post-transcriptional regulators of gene expression by base-pairing with their target mRNAs. To date, several hundred miRNAs have been described in hu Read More >

A novel behavioral bioassay for preclinical testing and characterization of CNS agents

Background Animal models of human diseases of the CNS occupy a central role in drug discovery yet these models fail to yield new insights and efficacious drugs for the treatment of these diseases, in a field having a collective economic cost of ov Read More >

Self Assembled Peptide Hydrogel

The Technology A breakthrough Self Assembled Peptide Hydrogel (SAPH) has been developed. SAPH is a safe, self-assembled, biocompatible, remarkably strong hydrogel with modulated stability that is suitable for various medicinal and cosmetic applicati Read More >

A novel heterologous overexpression system for mammalian membrane protein expression, purification and crystallization

The Technology A bacterial cloning and expression system for heterogeneous membrane protein expression (mammalian, bacterial) has been developed.  It yields significantly higher expression of heterogeneous membrane proteins in bacterial cells, Read More >

Leading Researchers:

Novel ALS biomarkers:Towards diagnostics and potential therapy

The TechnologyNovel ALS biomarkers, differentially expressed in blood and bone marrow samples from ALS patients have been identified. These are Cytoplasmic FMR Interacting Protein 2 (CyFIP2) and Retinoblastoma (Rb) Binding Protein 9 (RbBP9).  Bo Read More >

Leading Researchers:

ZZ-PE38: a universal technology for immunotherapy

The TechnologyA novel fusion protein capable of binding to any internalizing IgG, thus forming a specific and potent immunotoxin, has been developed. The antibody-toxin conjugate is formed through an immuno-complex and may be further stabilized by ch Read More >

Leading Researchers:

Silencing of Mortalin with siRNA as adjuvant for cancer immunotherapy

TechnologyA novel mode of treatment by inhibition of mortalin or mortalin synthesis as an adjuvant to antibodybased immunotherapy.Novel siRNA was designed as blocker of Mortalin expression. The anti-mortalin siRNA binds specifically to mortalin mRNA Read More >

Targeting bone neoplasms and other cancers with novel combined anticancer and anti-angiogenic polymer therapeutics

Anti-cancer NanoTherapyUtilizing unique nano-technology to develop targeted combination nanomedicines that were shown to be synergistic, effective and safe for treating cancer TechnologyWe have developed a new platform technology for the treatment o Read More >

Leading Researchers:

Immunotherapy for the prevention and treatment of osseous metastasis

Technology SVEP1 is a novel cell adhesion protein.  Its expression is primarily associated with bone cells but is also expressed by breast carcinoma cells.  Anti-SVEP1 antibodies block cell adhesion in in vitro matrix.  Prevention of Read More >